Methyl 2-Aminonicotinate is used to prepare 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827)as a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. It is also used to synthesize quinazolinone/quinazoline thione derivatives as phosphodiesterase 7 inhibitors.

CAS：14667-47-1
中文别名：2-氨基吡啶-3-甲酸甲酯;
英文别名：methyl 2-aminopyridine-3-carboxylate;Methyl 2-Aminopyridine-3-carboxylate;2-Aminonicotinic Acid Methyl Ester;2-Aminopyridine-3-carboxylic Acid Methyl Ester;Methyl 2-AMinonicotinate;
分子式：C7H8N2O2
分子量：152.151
精确质量：152.059
Psa：65.21
Logp：1.0316

密度：1.238g/cm3
沸点：251.3ºC at 760mmHg
熔点：84-86 °C
闪点：105.8ºC
折射率：1.57
蒸汽压：0.0206mmHg at 25°C

安全说明：S22-S26-S36/37/39
危险类别码：R20/21/22; R36/37/38
海关编码：2933399090
危险品标志：Xn