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化合物简介
                2-Cyanophenylboronic Acid is used in the synthesis of pyridine inhibitors of TAK1. Also participates in the discovery and synthesis of 1,2,4-triazoles as novel allosteric valosine containing protein (VCP) inhibitors. VCP is found highly abundant in various tumor types allowing for a potential target in cancer therapy.
            
            基本信息
                CAS:138642-62-3
中文别名:邻氰基苯硼酸;
英文别名:(2-cyanophenyl)boronic acid;2-Cyanophenylboronic Acid;2-Cyanobenzeneboronic acid;(2-Cyanophenyl)boronic acid;2-Cyanobenzeneboronic acid [m-Cyanophenyl-4-yl]boronic acid;
分子式:C7H6BNO2
分子量:146.939
精确质量:147.049
Psa:64.25
Logp:-0.76192
            中文别名:邻氰基苯硼酸;
英文别名:(2-cyanophenyl)boronic acid;2-Cyanophenylboronic Acid;2-Cyanobenzeneboronic acid;(2-Cyanophenyl)boronic acid;2-Cyanobenzeneboronic acid [m-Cyanophenyl-4-yl]boronic acid;
分子式:C7H6BNO2
分子量:146.939
精确质量:147.049
Psa:64.25
Logp:-0.76192
编号系统
                                    MDL号:MFCD01632208
PubChem号:24874204
                            
            PubChem号:24874204
物化性质
                                    外观与性状:灰白色至奶油色粉末
密度:1.25g/cm3
沸点:376.4ºC at 760mmHg
熔点:240°C (dec.)(lit.)
闪点:181.4ºC
折射率:1.559
蒸汽压:2.47E-06mmHg at 25°C
                            
            密度:1.25g/cm3
沸点:376.4ºC at 760mmHg
熔点:240°C (dec.)(lit.)
闪点:181.4ºC
折射率:1.559
蒸汽压:2.47E-06mmHg at 25°C
安全信息
                                    安全说明:S26-S36/37/39-S37/39
WGK Germany:3
危险类别码:R36/37/38
危险品运输编码:3439
海关编码:2931900090
危险品标志:Xi
                   
            
            WGK Germany:3
危险类别码:R36/37/38
危险品运输编码:3439
海关编码:2931900090
危险品标志:Xi
生产方法及用途
合成路线
- 
                            参考文献Journal of the American Chemical Society, , vol. 127, # 30 p. 10539 - 10544 
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