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化合物简介
Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is used for the control of delayed CINV—nausea and vomiting and there are tentative data to suggest that it may be more effective than granisetron.
基本信息
CAS:135729-61-2
中文别名:
英文别名:2-Qhbiqo;1H-Benz[de]isoquinolin-1-one, 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-, [S-(R*,R*)]-, hydrochloride;
分子式:C19H25ClN2O
分子量:332.868
精确质量:332.166
Psa:23.55
Logp:3.3343
中文别名:
英文别名:2-Qhbiqo;1H-Benz[de]isoquinolin-1-one, 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-, [S-(R*,R*)]-, hydrochloride;
分子式:C19H25ClN2O
分子量:332.868
精确质量:332.166
Psa:23.55
Logp:3.3343
编号系统
UNII:5D06587D6R
物化性质
密度:1.24 g/cm3
沸点:470.4ºC at 760 mmHg
沸点:470.4ºC at 760 mmHg
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict

