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化合物简介
Verteporfin (trade name Visudyne), a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 689nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.
基本信息
CAS:129497-78-5
中文别名:微替泊芬;
英文别名:Verteprofin;Verteporphin;trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester;Visudyne;VERTEPORFIN (200 MG);
分子式:C82H84N8O16
分子量:1437.59
精确质量:1436.6
Psa:337.48
Logp:10.246
中文别名:微替泊芬;
英文别名:Verteprofin;Verteporphin;trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester;Visudyne;VERTEPORFIN (200 MG);
分子式:C82H84N8O16
分子量:1437.59
精确质量:1436.6
Psa:337.48
Logp:10.246
编号系统
UNII:0X9PA28K43
物化性质
外观与性状:暗绿色至黑色固体
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict
