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化合物简介
Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI). It is the most important active metabolite of the widely used antidepressant fluoxetine, but little is known about its pharmacological actions. Seproxetine was being investigated by Eli Lilly and Company as an antidepressant; however, a cardiac side effect was noted and development was discontinued.
基本信息
CAS:126924-38-7
中文别名:
英文别名:UNII-25CO3X0R31;SEPROXETINE;
分子式:C16H16F3NO
分子量:295.3
精确质量:295.118
Psa:35.25
Logp:4.8746
中文别名:
英文别名:UNII-25CO3X0R31;SEPROXETINE;
分子式:C16H16F3NO
分子量:295.3
精确质量:295.118
Psa:35.25
Logp:4.8746
编号系统
物化性质
密度:1.204g/cm3
沸点:381.1ºC at 760 mmHg
闪点:184.3ºC
折射率:1.525
蒸汽压:5.21E-06mmHg at 25°C
沸点:381.1ºC at 760 mmHg
闪点:184.3ºC
折射率:1.525
蒸汽压:5.21E-06mmHg at 25°C
安全信息
海关编码:2922299090
生产方法及用途
合成路线
-
参考文献
HUMAN BIOMOLECULAR RESEARCH INSTITUTE Patent: WO2006/25920 A2, 2006 ; Location in patent: Page/Page column 148-149 ; WO 2006/025920 A2
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
