化学科研者一站式服务平台
-
1-羟基-2-(咪唑-1-基)-亚乙基-1,1-二磷酸一水化物
9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
化合物简介
CH5424802 is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. CH5424802 have been clinically evaluated for the treatment of patients with ALK-driven tumors.
基本信息
CAS：1256580-46-7
中文别名：9-乙基-6,6-二甲基-8-(4-吗啉哌啶-1-基)-11-氧代-6,11-二氢-5H-苯并[b]咔唑-3-甲腈;
英文别名：Alectinib;9-ethyl-6,11-dihydro-6,6-dimethyl-8-(4-(4-morpholinyl)-1-piperidinyl)-11-oxo-5h-benzo(b)carbazole-3-carbonitrile;9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile;AF802;UNII-LIJ4CT1Z3Y;
分子式：C30H34N4O2
分子量：482.617
精确质量：482.268
Psa：72.36
Logp：4.77618
中文别名：9-乙基-6,6-二甲基-8-(4-吗啉哌啶-1-基)-11-氧代-6,11-二氢-5H-苯并[b]咔唑-3-甲腈;
英文别名：Alectinib;9-ethyl-6,11-dihydro-6,6-dimethyl-8-(4-(4-morpholinyl)-1-piperidinyl)-11-oxo-5h-benzo(b)carbazole-3-carbonitrile;9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile;AF802;UNII-LIJ4CT1Z3Y;
分子式：C30H34N4O2
分子量：482.617
精确质量：482.268
Psa：72.36
Logp：4.77618
编号系统
MDL号：MFCD19440988
物化性质
密度：1.28
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
