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化合物简介
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period (physiology) of myocardial cells. Because of its Class III antiarrhythmic activity, there should not be concomitant administration of Class Ia and Class III agents.
基本信息
CAS:122647-32-9
中文别名:伊布利特;N-[4-[4-(乙基庚基胺)-1-羟基丁基]苯基]甲磺酰胺富马酸盐;伊布利特半富马酸盐;
英文别名:Ibutilide hemifumarate salt;Ibutilide fumarate;Ibutilide Fumarate;
分子式:C44H76N4O10S2
分子量:885.225
精确质量:884.5
Psa:230.64
Logp:10.3474
中文别名:伊布利特;N-[4-[4-(乙基庚基胺)-1-羟基丁基]苯基]甲磺酰胺富马酸盐;伊布利特半富马酸盐;
英文别名:Ibutilide hemifumarate salt;Ibutilide fumarate;Ibutilide Fumarate;
分子式:C44H76N4O10S2
分子量:885.225
精确质量:884.5
Psa:230.64
Logp:10.3474
编号系统
UNII:9L5X4M5L6I
物化性质
沸点:522.4ºC at 760 mmHg
闪点:269.7ºC
蒸汽压:9.71E-12mmHg at 25°C
闪点:269.7ºC
蒸汽压:9.71E-12mmHg at 25°C
安全信息
信号词:Warning
危险标志:GHS07
危险性描述:H302
危险标志:GHS07
危险性描述:H302