化学科研者一站式服务平台


  • Avibactam; 硫酸单[(1R,2S,5R)-2-(氨基羰基)-7-氧代-1,6-氮杂双环[3.2.1]辛-6-基]酯

    avibactam

化合物简介

Avibactam is a non-β-lactam β-lactamase inhibitor developed by Actavis (now Allergan) jointly with AstraZeneca. A new drug application for avibactam in combination with ceftazidime (branded as Avycaz) was approved by the FDA on February 25, 2015, for treating complicated urinary tract (cUTI) and complicated intra-abdominal infections (cIAI) caused by antibiotic resistant-pathogens, including those caused by multi-drug resistant Gram-negative bacterial pathogens.

基本信息

CAS:1192500-31-4
中文别名
英文别名:(2S,5R)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbox amide;(E)-7-fluoro-3-methylhept-4-en-2-one;trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide;4-Hepten-2-one,7-fluoro-3-methyl-,(E);trans-7-fluoro-3-methyl-4-hepten-2-one;
分子式:C7H11N3O6S
分子量:265.244
精确质量:265.037
Psa:139.61
Logp:0.581

编号系统

物化性质

密度:1.9±0.1g/cm3
折射率:1.679
储存条件:-20°C

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


加载中...