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化合物简介
N-Fmoc-D-serine is an N-Fmoc-protected form of D-Serine. D-Serine is a neurotransmitter that is concentrated in the mammalian brain, and is one of the very few amino acids that occur in the D- and L-configurations in significant amounts. D-Serine is an potent agonist of the N-methyl-D-aspartate (NMDA) receptor in the brain, which is associated with schizophrenia. Use of D-Serine has been considered as an additional therapy for refractory schizophrenic patients.
基本信息
CAS:116861-26-8
中文别名:FMOC-D-丝氨酸;芴甲氧羰基-D-丝氨酸;N-[(9H-芴-基甲氧基)羰基]-D-丝氨酸;N-(9-芴甲氧羰基)-D-丝氨酸;
英文别名:Fmoc-D-Ser-OH;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-serine;N-Fmoc-D-serine;Fmoc-D-serine;fmoc-Ser-OH;
分子式:C18H17NO5
分子量:327.331
精确质量:327.111
Psa:95.86
Logp:2.3615
中文别名:FMOC-D-丝氨酸;芴甲氧羰基-D-丝氨酸;N-[(9H-芴-基甲氧基)羰基]-D-丝氨酸;N-(9-芴甲氧羰基)-D-丝氨酸;
英文别名:Fmoc-D-Ser-OH;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-serine;N-Fmoc-D-serine;Fmoc-D-serine;fmoc-Ser-OH;
分子式:C18H17NO5
分子量:327.331
精确质量:327.111
Psa:95.86
Logp:2.3615
编号系统
MDL号:MFCD00077068
PubChem号:24871112
BRN号:4715790
PubChem号:24871112
BRN号:4715790
物化性质
密度:1.362g/cm3
沸点:599.3ºC at 760 mmHg
熔点:108-112ºC
闪点:316.2ºC
储存条件:2-8ºC
蒸汽压:3.27E-15mmHg at 25°C
沸点:599.3ºC at 760 mmHg
熔点:108-112ºC
闪点:316.2ºC
储存条件:2-8ºC
蒸汽压:3.27E-15mmHg at 25°C
安全信息
安全说明:S22-S24/25
海关编码:2924299090
海关编码:2924299090
生产方法及用途
合成路线
上游原料
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图谱
1H NMR : Predict

13C NMR : Predict
