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化合物简介
Aflatoxin B1 is an aflatoxin produced by Aspergillus flavus and A. parasiticus. It is arguably the most potent carcinogen known, and is up to twice as carcinogenic as an equitoxic dose of X-rays. Aflatoxin B1 is a common contaminant in a variety of foods including peanuts, cottonseed meal, corn, and other grains; as well as animal feeds. Aflatoxin B1 is considered the most toxic aflatoxin and it is highly implicated in hepatocellular carcinoma (HCC) in humans. In animals, aflatoxin B1 has also been shown to be mutagenic, teratogenic, and to cause immunosuppression. Several sampling and analytical methods including thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), mass spectroscopy, and enzyme-linked immunosorbent assay (ELISA), among others, have been used to test for aflatoxin B1 contamination in foods. According to the Food and Agriculture Organization (FAO), the worldwide maximum tolerated levels of aflatoxin B1 was reported to be in the range of 1–20 µg/kg in food, and 5–50 µg/kg in dietary cattle feed in 2003.
基本信息
CAS:1162-65-8
中文别名:黄曲霉毒素B1;黄曲霉毒素 B1;
英文别名:AFLATOXIN B1;Aflatoxin B1 Crystalline;Aflatoxin B1;Aflatoxin B1, crystalline;
分子式:C17H12O6
分子量:312.274
精确质量:312.063
Psa:74.97
Logp:2.2765
中文别名:黄曲霉毒素B1;黄曲霉毒素 B1;
英文别名:AFLATOXIN B1;Aflatoxin B1 Crystalline;Aflatoxin B1;Aflatoxin B1, crystalline;
分子式:C17H12O6
分子量:312.274
精确质量:312.063
Psa:74.97
Logp:2.2765
编号系统
RTECS号:GY1925000
BRN号:1269174
MDL号:MFCD00869647
PubChem号:24891116
EINECS号:214-603-3
BRN号:1269174
MDL号:MFCD00869647
PubChem号:24891116
EINECS号:214-603-3
物化性质
熔点:268-269 °C
安全信息
安全说明:53-45-36-26-16-24-7
危险类别码:R45; R46; R26/27/28; R36; R20/21/22; R11; R65; R48/23/24/25; R36/38; R39/23/24/25; R23/24/25
危险品运输编码:UN 3462 6.1/PG 1
危险类别码:R45; R46; R26/27/28; R36; R20/21/22; R11; R65; R48/23/24/25; R36/38; R39/23/24/25; R23/24/25
危险品运输编码:UN 3462 6.1/PG 1
生产方法及用途
合成路线
上游原料
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图谱
13C NMR : Predict

1H NMR : Predict
