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  • L-䓝基乙醛酸酯水合物

    L-Menthyl glyoxylate hydrate

化合物简介

L-Menthyl 2,2-Dihydroxyacetate is used as a reagent in the synthesis of Lamivudine; a potent nucleoside reverse transcriptase inhibitor used for the treatment of chronic hepatitis B. L-Menthyl 2,2-Dihydroxyacetate is also used as a reagent in the synthesis of 4-acetoxy-3-hydroxyethylazetidin-2-one, a key intermediate for the preparation of penem and carbapenem antibiotics.

基本信息

CAS:111969-64-3
中文别名:乙醛酸薄荷酯水合物;L-孟基乙醛酸酯水合物;水合乙醛酸薄荷酯;拉米夫定中间体L-MGH;2,2-二羟基醋酸-(1R,2S,5R)-2-异丙基-5-甲基环己酯;(1S)-(+)-孟基乙醛酸水合物;䓝基乙醛酸水合物;5-甲基-2-异丙基环己醇二羟基乙酸酯;
英文别名:(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2,2-Dihydroxyacetate;(1R)-(-)-Menthyl glyoxylate monohydrate;L-menthyl glyoxylate;2,2-Dihydroxyacetic acid (-)-menthyl ester;L-MENTHYL 2,2-DIHYDROXYACETATE;L-Menthyl glyoxylate monohydrate;(-)-menthyl glyoxylate hydrate;L-Menthyl Glyoxylate Hydrate;2,2-Dihydroxyacetic Acid (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ester;Glyoxylic acid (1S)-menthyl ester hydrate;(-)-Menthyl 2,2-Dihydroxyacetate;L-MGH;Acetic acid, dihydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester;Acetic acid, dihydroxy-, 5-methyl-2-(1-methylethyl)cyclohexyl ester, [1R-(1α,2β,5α)]-;2,2-Dihydroxyacetic acid, (-)-menthyl ester;Acetic acid, 2,2-dihydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester;(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate;
分子式:C12H22O4
分子量:230.301
精确质量:230.152
Psa:66.76
Logp:1.3011

编号系统

MDL号:MFCD04037548
BRN号:4905777
EINECS号:000-000-0

物化性质

密度:1.09
沸点:320 °C
熔点:80-81 °C
闪点:113 °C
折射率:1.487
蒸汽压:2.74E-05mmHg at 25°C

安全信息

安全说明:S61-S36/39-S26-S22
危险类别码:R51/53
危险品运输编码:3077
危险类别:9
包装等级:III
危险品标志:Xn; N

生产方法及用途

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Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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