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ASP 3026; N2-[2-甲氧基-4-[4-(4-甲基-1-哌嗪基)-1-哌啶基]苯基]-N4-[2-[(1-甲基乙基)磺酰基]苯基]-1,3,5-三嗪-2,4-二胺
2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
化合物简介
ASP3026 is a novel and selective anaplastic lymphoma kinase (ALK) inhibitor that shows potent anti-tumor activities. ASP3026 also shows potential efficacy for non-small cell lung cancer (NSCLC) and is expected to improve the therapeutic outcomes of patients with cancer with ALK abnormality.
基本信息
CAS：1097917-15-1
中文别名：
英文别名：CS-0787;QCR-144;N-[2-(isopropylsulfonyl)phenyl]-N\'-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-1,3,5-triazine-2,4-diamine;N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-N\'-[2-(propane-2-sulfonyl)phenyl]-1,3,5-triazine-2,4-diamine;ASP 3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine;UNII-HP4L6MXF10;
分子式：C29H40N8O3S
分子量：580.745
精确质量：580.294
Psa：127.43
Logp：4.2822
中文别名：
英文别名：CS-0787;QCR-144;N-[2-(isopropylsulfonyl)phenyl]-N\'-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-1,3,5-triazine-2,4-diamine;N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-N\'-[2-(propane-2-sulfonyl)phenyl]-1,3,5-triazine-2,4-diamine;ASP 3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine;UNII-HP4L6MXF10;
分子式：C29H40N8O3S
分子量：580.745
精确质量：580.294
Psa：127.43
Logp：4.2822
编号系统
MDL号：MFCD21609265
物化性质
密度：1.3±0.1g/cm3
沸点：794.3±70.0°Cat760mmHg
闪点：434.2±35.7°C
蒸汽压：0.0±2.8mmHgat25°C
折射率：1.620
储存条件：-20°C
沸点：794.3±70.0°Cat760mmHg
闪点：434.2±35.7°C
蒸汽压：0.0±2.8mmHgat25°C
折射率：1.620
储存条件：-20°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
