AZD 6244 and MK 2206 are targeted small-molecule drugs that inhibit MEK and AKT responses. The combination of AZD6244 and MK2206 has a significant synergistic effect on tumor growth in vitro and in vivo and leads to increased survival rates in mice bearing highly aggressive human lung tumors. Antitumor agents.

CAS：1032350-13-2
中文别名：8-[4-(1-氨基环丁基)苯基]-9-苯基-1,2,4-噻唑并[3,4-f][1,6]萘啶-3(2H)-酮双盐酸盐;
英文别名：
分子式：C25H23Cl2N5O
分子量：480.389
精确质量：479.128
Psa：89.07
Logp：6.547

UNII：Q34I3E28IO