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化合物简介
Fadrozole (INN, marketed as Afema by Novartis) is a selective aromatase inhibitor that has been introduced in Japan for the treatment of breast cancer.
基本信息
CAS：102676-31-3
中文别名：
英文别名：4-(5,6,7,8-TETRAHYDROIMIDAZO[1,5-A]PYRIDIN-5-YL)BENZONITRILE HYDROCHLORIDE;4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile;Fadrazole;4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride;FADROZOLE HCL;+-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine hydrochloride;4-(5,6,7,8-tetrahydro-imidazo-[1,5a]-pyridin-5-yl)benzonitrile monohydrochloride;fadrozole hydrochloride;5-(4-cyanophenyl)-5,6,7,8-tetrahydroimidazo<1,5-a>pyridine;
分子式：C14H14ClN3
分子量：259.734
精确质量：259.088
Psa：41.61
Logp：3.48248
中文别名：
英文别名：4-(5,6,7,8-TETRAHYDROIMIDAZO[1,5-A]PYRIDIN-5-YL)BENZONITRILE HYDROCHLORIDE;4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile;Fadrazole;4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride;FADROZOLE HCL;+-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine hydrochloride;4-(5,6,7,8-tetrahydro-imidazo-[1,5a]-pyridin-5-yl)benzonitrile monohydrochloride;fadrozole hydrochloride;5-(4-cyanophenyl)-5,6,7,8-tetrahydroimidazo<1,5-a>pyridine;
分子式：C14H14ClN3
分子量：259.734
精确质量：259.088
Psa：41.61
Logp：3.48248
编号系统
RTECS号：DI4952500
MDL号：MFCD00866239
MDL号：MFCD00866239
物化性质
沸点：481.7ºC at 760mmHg
闪点：245.1ºC
蒸汽压：1.95E-09mmHg at 25°C
闪点：245.1ºC
蒸汽压：1.95E-09mmHg at 25°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
