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化合物简介

Triclocarban is an antibacterial agent common in personal care products like soaps and lotions as well as in the medical field, for which it was originally developed. Studies on its antibacterial qualities and mechanisms are growing. Research suggests that it is similar in its mechanism to triclosan and is effective in fighting infections by targeting the growth of bacteria such as Staphylococcus aureus. Additional research seeks to understand its potential for causing antibacterial resistance and its effects on organismal and environmental health.

基本信息

CAS:101-20-2
中文别名:N-(4-氯苯基)-N’-(3,4-二氯苯基)脲;
英文别名:3,4,4\'-Trichlorocarbanilide;3,4,4′-Trichlorocarbanilide;3,4,4\'-Trichlorodiphenylurea;cusiter;Triclocarban;Nobacter;genoface;Procutene;TCC;CUTISAN;3,4,4‘-Trichlorocarbanilide;1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea;3,4,4-Trichlorocarbanilide;
分子式:C13H9Cl3N2O
分子量:315.582
精确质量:313.978
Psa:41.13
Logp:5.4368

编号系统

EINECS号:202-924-1
MDL号:MFCD00013254
RTECS号:FE1250000
PubChem号:24846715

物化性质

外观与性状:白色细粉末
密度:1.534 g/cm3
沸点:344.2ºC at 760 mmHg
熔点:254-256°C(lit.)
闪点:150°C
折射率:1.699
稳定性:Stable. Combustible. Incompatible with strong oxidizing agents strong bases.
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:0.000374mmHg at 25°C

安全信息

RTECS号:FE1250000
安全说明:S60; S61
危险类别码:R50/53
WGK Germany:2
海关编码:2924299090
危险品运输编码:UN 3077 9/PG 3
危险品标志:N

生产方法及用途

用途
三氯卡班TCC作为一种高效、广谱、安全的新型抗菌剂,在医疗消毒剂中有着广泛应用。

合成路线

上游原料

下游产品

图谱

Predict 1H proton NMR


Mass


IR : KBr disc


IR : nujol mull


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