LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs.

CAS：1005342-46-0
中文别名：
英文别名：N1-(1H-benzimidazol-2-ylmethyl)-N1-(5,6,7,8-tetrahydro-quinolin-8-yl)-butane-1,4-diamine;(S)-(N\'-(1H-benzimidazol-2-ylmethyl)-N\'-(5,6,7,8-tetrahydroquinolin-8-yl))-1,4-butanediamine;(S)-N\'-((1H-benzo[d]imidazol-2-yl)methyl)-N\'-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine;(S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide;(S)-N\'-(1H-benzimidazol-2-ylmethyl)-N\'-(5,6,7,8-tetrahydro-quinolin-8-yl)-butane-1,4-diamine;N\'-(1H-benzimidazol-2-ylmethyl)-N\'-(S)-5,6,7,8-tetrahydro-quinolin-8-yl-butane-1,4-diamine;(S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine;AMD 070;Propanamide, N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-, (2S)-;N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N²-methylalaninamide;
分子式：C26H33FN4O3S
分子量：500.629
精确质量：500.226
Psa：123.13
Logp：5.0188

MDL号：MFCD23160049

外观与性状：米色至黄色固体