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化合物简介
HA-966 or (±) 3-Amino-1-hydroxy-pyrrolidin-2-one is a molecule used in scientific research as a glycine receptor and NMDA receptor antagonist / low efficacy partial agonist. It has neuroprotective and anticonvulsant, anxiolytic, antinociceptive and sedative / hypnotic effects in animal models. Pilot human clinical trials in the early 1960s showed that HA-966 appeared to benefit patients with tremors of extrapyramidal origin.
基本信息
CAS:1003-51-6
中文别名:
英文别名:1-dodecyl-hexahydro-azepin-2-one;tranzone;1dodecylhexahydro-2H-azepin-2-one;1-N-dodecylazacycloheptan-2-one;acecloguanosine;usafnd-72;1 hydroxy 3 aminopyrrolid 2 one;Azone,Laurocapram;1 dodecylperhydroazepin 2 one;azon;Lauocapram;AZONE;
分子式:C4H8N2O2
分子量:116.119
精确质量:116.059
Psa:66.56
Logp:-0.4266
中文别名:
英文别名:1-dodecyl-hexahydro-azepin-2-one;tranzone;1dodecylhexahydro-2H-azepin-2-one;1-N-dodecylazacycloheptan-2-one;acecloguanosine;usafnd-72;1 hydroxy 3 aminopyrrolid 2 one;Azone,Laurocapram;1 dodecylperhydroazepin 2 one;azon;Lauocapram;AZONE;
分子式:C4H8N2O2
分子量:116.119
精确质量:116.059
Psa:66.56
Logp:-0.4266
编号系统
MDL号:MFCD00069208
物化性质
密度:1.436g/cm3
沸点:258.6ºC at 760mmHg
闪点:110.2ºC
折射率:1.59
蒸汽压:0.002mmHg at 25°C
沸点:258.6ºC at 760mmHg
闪点:110.2ºC
折射率:1.59
蒸汽压:0.002mmHg at 25°C
安全信息
安全说明:S26
危险类别码:R36/37/38
海关编码:2933790090
危险品标志:Xi
危险类别码:R36/37/38
海关编码:2933790090
危险品标志:Xi
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
